Karamakate, is an Amazonian shaman and the last survivor of his people. Together with two scientists with whom he has built a friendship over 40 years, he searches for the sacred and rare psychedelic Yakruna plant. Tracking two parallel odysseys through the Amazon, this blistering and poetic historic epic examines the ravages of colonialism which cast a dark shadow over the South American landscape. The film was nominated at the Academy Awards in 2016 for Best Foreign Language Film.